Basic Information
ID: ALA4843806
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in Escherichia coli incubated for 30 mins by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Bromodomain-containing protein 4(ALA1163125)
Document: ALA4842350
Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in Escherichia coli incubated for 30 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843806
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.43 | 3.60 | 3.60 |
| 415.45 | 4.16 | 4.16 |
| 364.41 | 3.57 | 3.57 |
| 427.51 | 5.43 | 5.43 |
| 400.44 | 3.89 | 3.89 |
| 432.52 | 5.17 | 5.17 |
| 490.60 | 5.75 | 5.75 |
| 469.55 | 5.20 | 5.20 |
| 450.54 | 4.97 | 4.97 |
| 366.42 | 3.81 | 3.81 |
| 421.50 | 3.50 | 3.50 |
| 408.46 | 3.58 | 3.58 |
| 429.48 | 4.45 | 4.45 |
| 381.44 | 2.72 | 2.72 |
| 394.43 | 3.19 | 3.19 |
| 477.57 | 4.13 | 4.13 |
| 410.47 | 4.22 | 4.22 |
| 399.45 | 4.62 | 4.62 |
| 413.48 | 4.87 | 4.87 |
| 380.45 | 4.52 | 4.52 |
| 393.45 | 3.08 | 3.08 |
| 352.39 | 3.74 | 3.74 |
| 422.49 | 4.15 | 4.15 |
| 394.43 | 3.51 | 3.51 |
| 382.42 | 3.37 | 3.37 |
| 435.53 | 4.36 | 4.36 |
| 427.51 | 5.26 | 5.26 |
| 458.52 | 4.37 | 4.37 |
| 472.55 | 4.93 | 4.93 |
| 436.51 | 4.44 | 4.44 |
| 450.54 | 4.97 | 4.97 |
| 408.46 | 3.58 | 3.58 |
| 450.54 | 4.97 | 4.97 |