Basic Information
ID: ALA4843816
Type: ADME
Description: Time dependent inhibition of recombinant human CYP2D6 expressed in Escherichia coli using MMC as probe substrate preincubated for 10 mins followed by NADPH-regenerating system addition and measured at 1 min interval for 30 mins by fluorescence plate reader analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Cytochrome P450 2D6(ALA289)
Document: ALA4842350
Time dependent inhibition of recombinant human CYP2D6 expressed in Escherichia coli using MMC as probe substrate preincubated for 10 mins followed by NADPH-regenerating system addition and measured at 1 min interval for 30 mins by fluorescence plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843816
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.54 | 4.97 | 4.97 |