Basic Information
ID: ALA4843875
Type: Binding
Description: Inhibition of full-length N-terminal GST tagged BTK (1 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: Tyrosine-protein kinase BTK(ALA5251)
Document: ALA4842353
Inhibition of full-length N-terminal GST tagged BTK (1 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as substrate preincubated for 1 hr followed by ATP addition and measured after 2 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843875
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.51 | 4.22 | 4.22 |
| 471.56 | 4.22 | 4.22 |
| 463.50 | 5.01 | 5.01 |
| 485.54 | 4.12 | 4.12 |
| 483.57 | 4.89 | 4.89 |
| 439.48 | 3.17 | 3.17 |
| 427.46 | 3.29 | 3.29 |
| 457.47 | 3.31 | 3.31 |
| 483.53 | 3.57 | 3.57 |
| 483.57 | 4.89 | 4.89 |
| 457.47 | 3.31 | 3.31 |
| 443.44 | 2.92 | 2.92 |
| 457.49 | 3.34 | 3.34 |
| 481.56 | 4.26 | 4.26 |
| 483.53 | 3.57 | 3.57 |
| 471.49 | 3.70 | 3.70 |
| 445.45 | 3.47 | 3.47 |
| 473.51 | 4.25 | 4.25 |
| 469.50 | 3.18 | 3.18 |
| 489.48 | 3.84 | 3.84 |
| 469.55 | 4.50 | 4.50 |
| 471.52 | 3.73 | 3.73 |
| 485.52 | 4.09 | 4.09 |
| 481.56 | 3.96 | 3.96 |
| 485.54 | 4.12 | 4.12 |
| 427.46 | 3.33 | 3.33 |
| 455.52 | 4.11 | 4.11 |
| 425.45 | 2.78 | 2.78 |
| 483.53 | 3.57 | 3.57 |
| 441.49 | 3.68 | 3.68 |
| 459.48 | 3.86 | 3.86 |
| 469.55 | 4.50 | 4.50 |
| 546.43 | 4.71 | 4.71 |
| 497.56 | 3.96 | 3.96 |
| 532.40 | 4.32 | 4.32 |
| 455.47 | 2.79 | 2.79 |
| 485.52 | 4.09 | 4.09 |
| 534.41 | 4.88 | 4.88 |
| 441.49 | 3.33 | 3.33 |
| 457.47 | 3.31 | 3.31 |
| 471.49 | 3.70 | 3.70 |
| 426.48 | 3.88 | 3.88 |
| 467.53 | 3.87 | 3.87 |
| 441.49 | 3.72 | 3.72 |
| 491.50 | 4.39 | 4.39 |
| 469.55 | 4.42 | 4.42 |
| 483.53 | 3.57 | 3.57 |
| 471.49 | 3.70 | 3.70 |
| 453.50 | 3.56 | 3.56 |
| 473.51 | 4.25 | 4.25 |
| 469.50 | 3.18 | 3.18 |
| 453.50 | 3.56 | 3.56 |
| 459.48 | 3.86 | 3.86 |
| 469.55 | 4.12 | 4.12 |
| 482.54 | 3.14 | 3.14 |
| 497.56 | 3.96 | 3.96 |
| 473.51 | 4.25 | 4.25 |
| 469.50 | 3.18 | 3.18 |
| 471.49 | 3.70 | 3.70 |
| 503.51 | 4.23 | 4.23 |
| 512.61 | 4.04 | 4.04 |
| 439.48 | 3.17 | 3.17 |
| 484.56 | 3.22 | 3.22 |
| 471.49 | 3.70 | 3.70 |
| 470.53 | 3.30 | 3.30 |
| 471.52 | 3.73 | 3.73 |
| 461.48 | 4.46 | 4.46 |
| 467.53 | 3.95 | 3.95 |
| 463.50 | 5.01 | 5.01 |