Basic Information
ID: ALA4843992
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of recombinant human full-length PARP-2 to IC50 for inhibition of recombinant human full-length PARP-1
Format: BAO_0000019
Organism: Homo sapiens
Target: Unchecked(ALA612545)
Document: ALA4842357
Selectivity index, ratio of IC50 for inhibition of recombinant human full-length PARP-2 to IC50 for inhibition of recombinant human full-length PARP-1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4843992
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.46 | 5.13 | 5.13 |
| 434.47 | 2.35 | 2.35 |
| 397.43 | 2.78 | 2.78 |
| 458.51 | 4.21 | 4.21 |
| 538.46 | 5.13 | 5.13 |
| 478.53 | 3.60 | 3.60 |
| 540.49 | 4.55 | 4.55 |
| 460.49 | 3.60 | 3.60 |
| 473.49 | 2.93 | 2.93 |
| 473.49 | 2.93 | 2.93 |
| 464.54 | 3.96 | 3.96 |
| 502.52 | 4.03 | 4.03 |
| 512.50 | 5.78 | 5.78 |
| 472.50 | 3.53 | 3.53 |
| 506.94 | 4.19 | 4.19 |
| 462.46 | 3.13 | 3.13 |
| 530.58 | 4.65 | 4.65 |
| 478.93 | 4.55 | 4.55 |
| 492.96 | 4.55 | 4.55 |
| 502.52 | 3.54 | 3.54 |
| 444.49 | 3.90 | 3.90 |
| 439.46 | 3.35 | 3.35 |
| 459.50 | 3.29 | 3.29 |
| 507.49 | 4.95 | 4.95 |
| 534.52 | 6.34 | 6.34 |
| 448.48 | 3.49 | 3.49 |
| 422.48 | 3.10 | 3.10 |
| 548.59 | 3.92 | 3.92 |
| 462.48 | 4.04 | 4.04 |
| 460.49 | 3.60 | 3.60 |
| 518.57 | 3.91 | 3.91 |
| 410.43 | 2.24 | 2.24 |
| 443.50 | 4.96 | 4.96 |
| 524.46 | 5.86 | 5.86 |
| 522.47 | 5.43 | 5.43 |
| 464.56 | 4.27 | 4.27 |
| 488.54 | 3.90 | 3.90 |
| 512.48 | 4.92 | 4.92 |
| 478.55 | 3.80 | 3.80 |
| 473.49 | 2.93 | 2.93 |
| 464.54 | 3.96 | 3.96 |
| 436.46 | 2.63 | 2.63 |
| 520.49 | 6.03 | 6.03 |
| 450.49 | 3.02 | 3.02 |
| 438.48 | 2.88 | 2.88 |
| 496.43 | 5.32 | 5.32 |
| 425.44 | 2.96 | 2.96 |
| 446.46 | 2.69 | 2.69 |
| 452.51 | 2.87 | 2.87 |
| 476.50 | 4.03 | 4.03 |
| 441.48 | 4.87 | 4.87 |
| 472.54 | 4.20 | 4.20 |
| 448.48 | 3.49 | 3.49 |
| 526.51 | 4.91 | 4.91 |
| 574.46 | 6.74 | 6.74 |
| 438.52 | 3.74 | 3.74 |