Basic Information
ID: ALA4844173
Type: Binding
Description: Inhibition of His6-tagged KRas G12V mutant (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as reduction in Ras/GST-fused Raf RBD interaction incubated for 1 hr by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4844173
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2135.43 | ||
| 2201.49 | ||
| 2216.54 | ||
| 2174.47 | ||
| 2144.44 | ||
| 2273.60 | ||
| 2206.51 | ||
| 2149.41 | ||
| 2192.48 | ||
| 2210.47 | ||
| 2192.48 | ||
| 2149.46 | ||
| 2208.48 | ||
| 2121.40 | ||
| 2149.46 | ||
| 2222.51 | ||
| 2240.52 | ||
| 2224.52 | ||
| 2230.53 | ||
| 2135.43 | ||
| 2185.48 | ||
| 2315.59 | ||
| 2125.37 | ||
| 2206.51 | ||
| 2253.51 | ||
| 1760.98 | ||
| 2218.47 | ||
| 2200.47 | ||
| 2135.39 | ||
| 2136.37 | ||
| 2178.45 | ||
| 2192.48 | ||
| 2153.40 | ||
| 2177.51 | ||
| 2312.59 | ||
| 2221.52 | ||
| 2281.59 | ||
| 2243.57 | ||
| 2181.47 | ||
| 2178.50 | ||
| 2151.43 | ||
| 2100.42 | ||
| 1931.20 | ||
| 2151.43 | ||
| 2135.43 | ||
| 2198.51 | ||
| 2165.46 | ||
| 2235.51 | ||
| 2295.62 | ||
| 2171.36 | ||
| 2121.40 | ||
| 2082.34 | ||
| 2153.42 | ||
| 2167.45 | ||
| 2295.62 | ||
| 2144.44 | ||
| 2220.53 | ||
| 2149.46 | ||
| 2214.53 | ||
| 2198.51 | ||
| 2169.83 | ||
| 1917.17 | ||
| 2219.51 | ||
| 2141.48 | ||
| 2226.93 |