Basic Information
ID: ALA4844246
Type: Binding
Description: Inhibition of human TRPM2 expressed in HEK293T cells cotransfected with GFP assessed as suppression of H2O2-induced calcium flux at 30 uM pretreated for 30 mins followed by H2O2 stimulation by Fluo-3/AM assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293T
Target: Transient receptor potential cation channel subfamily M member 2(ALA1250402)
Document: ALA4842361
Inhibition of human TRPM2 expressed in HEK293T cells cotransfected with GFP assessed as suppression of H2O2-induced calcium flux at 30 uM pretreated for 30 mins followed by H2O2 stimulation by Fluo-3/AM assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4844246
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 225.10 | ||
| 410.47 | 4.45 | 4.45 |
| 381.52 | 3.12 | 3.12 |
| 404.51 | 4.30 | 4.30 |
| 312.42 | 3.14 | 3.14 |