Basic Information
ID: ALA4844262
Type: Binding
Description: Potency index, ratio of donepezil IC50 to test compound IC50 for inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Acetylcholinesterase(ALA220)
Document: ALA4842362
Potency index, ratio of donepezil IC50 to test compound IC50 for inhibition of human recombinant AChE using acetylthiocholine iodide as a substrate preincubated for 20 mins followed by substrate addition by spectrophotometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4844262
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.14 | 7.03 | 7.03 |
| 523.12 | 5.99 | 5.99 |
| 562.15 | 7.87 | 7.87 |
| 556.18 | 6.73 | 6.73 |
| 506.09 | 7.39 | 7.39 |
| 547.14 | 7.15 | 7.15 |
| 561.17 | 7.75 | 7.75 |