Basic Information
ID: ALA4844300
Type: Binding
Description: Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by luciferase based assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4844300
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.43 | 3.51 | 3.51 |
| 415.47 | 7.05 | 7.05 |
| 424.51 | 5.06 | 5.06 |
| 457.58 | 6.17 | 6.17 |
| 448.57 | 5.77 | 5.77 |
| 413.43 | 5.72 | 5.72 |
| 470.53 | 5.74 | 5.74 |
| 465.58 | 6.42 | 6.42 |
| 448.57 | 5.77 | 5.77 |
| 494.55 | 5.92 | 5.92 |
| 469.54 | 6.25 | 6.25 |
| 469.49 | 7.00 | 7.00 |
| 512.54 | 5.98 | 5.98 |
| 465.53 | 5.28 | 5.28 |
| 469.49 | 7.00 | 7.00 |
| 439.47 | 6.99 | 6.99 |
| 399.40 | 5.71 | 5.71 |
| 453.50 | 6.45 | 6.45 |
| 425.44 | 6.69 | 6.69 |
| 448.57 | 5.77 | 5.77 |
| 493.63 | 7.23 | 7.23 |
| 469.49 | 7.00 | 7.00 |
| 511.55 | 6.57 | 6.57 |
| 487.53 | 6.39 | 6.39 |
| 492.63 | 6.25 | 6.25 |
| 452.54 | 5.60 | 5.60 |
| 484.55 | 5.56 | 5.56 |
| 469.54 | 6.25 | 6.25 |
| 452.54 | 5.60 | 5.60 |
| 490.66 | 6.76 | 6.76 |
| 509.63 | 6.90 | 6.90 |
| 495.54 | 5.34 | 5.34 |
| 452.54 | 5.60 | 5.60 |
| 441.51 | 5.70 | 5.70 |
| 499.52 | 7.01 | 7.01 |
| 469.54 | 6.25 | 6.25 |
| 465.58 | 6.42 | 6.42 |
| 465.58 | 6.42 | 6.42 |
| 487.53 | 6.39 | 6.39 |
| 440.58 | 5.53 | 5.53 |
| 476.63 | 6.59 | 6.59 |
| 507.66 | 7.41 | 7.41 |
| 451.55 | 6.11 | 6.11 |
| 437.47 | 5.24 | 5.24 |
| 333.34 | 5.32 | 5.32 |
| 434.55 | 5.47 | 5.47 |