Basic Information
ID: ALA4844385
Type: Binding
Description: Protac activity at VHL3/AR in human VCaP cells assessed as induction of AR degradation at 0.01 uM measured after 24 hrs by western blot analysis relative to control
Organism: Homo sapiens
Cell type: VCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA4844385
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 792.34 | 4.48 | 4.48 |
| 806.32 | 3.87 | 3.87 |
| 739.27 | 5.92 | 5.92 |
| 766.30 | 4.46 | 4.46 |
| 753.30 | 6.31 | 6.31 |
| 803.94 | 4.75 | 4.75 |
| 794.35 | 5.24 | 5.24 |
| 753.30 | 6.31 | 6.31 |
| 767.33 | 6.70 | 6.70 |
| 764.28 | 3.99 | 3.99 |
| 711.22 | 5.14 | 5.14 |
| 834.37 | 4.65 | 4.65 |
| 832.40 | 5.26 | 5.26 |
| 781.35 | 7.09 | 7.09 |
| 808.38 | 5.63 | 5.63 |
| 780.33 | 4.85 | 4.85 |
| 820.35 | 4.12 | 4.12 |
| 792.34 | 4.63 | 4.63 |
| 739.27 | 5.92 | 5.92 |
| 854.93 | 5.02 | 5.02 |
| 806.36 | 5.02 | 5.02 |
| 846.43 | 5.65 | 5.65 |
| 777.32 | 6.09 | 6.09 |
| 848.40 | 4.90 | 4.90 |
| 846.43 | 5.80 | 5.80 |
| 766.30 | 4.46 | 4.46 |
| 820.39 | 5.26 | 5.26 |
| 853.94 | 5.63 | 5.63 |
| 778.31 | 4.24 | 4.24 |
| 818.37 | 5.02 | 5.02 |
| 780.33 | 4.85 | 4.85 |
| 832.40 | 5.41 | 5.41 |
| 805.38 | 6.87 | 6.87 |
| 725.25 | 5.53 | 5.53 |
| 874.48 | 6.58 | 6.58 |
| 820.39 | 5.26 | 5.26 |
| 806.36 | 5.02 | 5.02 |
| 794.35 | 5.24 | 5.24 |