Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation at 10 uM incubated up to 48 hrs under shaking condition and me...

Basic Information

ID: ALA4844514

Type: Binding

Description: Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation at 10 uM incubated up to 48 hrs under shaking condition and measured every 3 min by Thioflavin T based fluorescence assay relative to control

Format: BAO_0000357

Organism: Homo sapiens

Target: Amyloid-beta A4 protein(ALA2487)

Document: ALA4842370

Inhibition of HFIP-pretreated human recombinant amyloid beta (1 to 42) self aggregation at 10 uM incubated up to 48 hrs under shaking condition and measured every 3 min by Thioflavin T based fluorescence assay relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4844514

Inhibition

Total(20)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
250.34	2.76	2.76
550.68	4.09	4.09
518.47	4.94	4.94
484.02	4.29	4.29
582.77	6.56	6.56
554.72	5.78	5.78
477.63	4.42	4.42
540.69	5.39	5.39
494.57	3.54	3.54
467.57	3.78	3.78
517.57	4.66	4.66
484.02	4.29	4.29
463.60	3.94	3.94
463.60	4.03	4.03
479.60	3.65	3.65
491.66	4.81	4.81
568.74	6.17	6.17
596.80	6.95	6.95
449.58	3.64	3.64
484.02	4.29	4.29