Basic Information
ID: ALA4844595
Type: Binding
Description: Protac activity at CRBN/AR in human VCaP cells assessed as maximal AR degradation after 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: VCaP
Activity Charts
Bioactivity
Activity Types for Assay ALA4844595
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 464.44 | 3.99 | 3.99 |
| 792.34 | 4.77 | 4.77 |
| 858.88 | 4.46 | 4.46 |
| 780.33 | 5.14 | 5.14 |
| 791.35 | 4.58 | 4.58 |
| 795.38 | 7.77 | 7.77 |
| 777.33 | 4.05 | 4.05 |
| 764.28 | 3.99 | 3.99 |
| 725.25 | 5.82 | 5.82 |
| 764.28 | 4.13 | 4.13 |
| 871.87 | 4.00 | 4.00 |
| 683.17 | 4.65 | 4.65 |
| 777.33 | 4.56 | 4.56 |
| 791.35 | 4.58 | 4.58 |
| 781.35 | 7.38 | 7.38 |
| 778.31 | 4.52 | 4.52 |
| 750.26 | 3.74 | 3.74 |
| 466.03 | 4.14 | 4.14 |
| 778.31 | 4.52 | 4.52 |
| 777.33 | 4.05 | 4.05 |
| 812.30 | 3.70 | 3.70 |
| 711.22 | 5.43 | 5.43 |
| 805.38 | 4.83 | 4.83 |
| 697.19 | 5.04 | 5.04 |
| 805.38 | 4.97 | 4.97 |
| 792.34 | 4.91 | 4.91 |
| 766.30 | 4.75 | 4.75 |
| 819.41 | 5.36 | 5.36 |
| 763.30 | 3.80 | 3.80 |
| 805.38 | 4.83 | 4.83 |
| 763.30 | 3.80 | 3.80 |
| 835.86 | 2.93 | 2.93 |
| 752.27 | 4.36 | 4.36 |
| 767.33 | 6.99 | 6.99 |
| 739.27 | 6.21 | 6.21 |
| 764.28 | 4.09 | 4.09 |
| 778.31 | 4.48 | 4.48 |
| 738.24 | 3.97 | 3.97 |
| 753.30 | 6.60 | 6.60 |