ID: ALA4844658
Type: Binding
Description: Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as reduction in AR protein level at 100 nM after 24 hrs in presence of N-((1r,4r)-4-((3-chloro-4-cyanophenyl)(methyl)amino)cyclohexyl)-4-(4-methylpiperazin-1-yl)benzamide by Western blot analysis
Organism: Homo sapiens
Cell type: LNCaP
Bioactivity
Activity Types for Assay ALA4844658
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
763.30 | 3.80 | 3.80 |