Assay Report Card

Basic Information

ID: ALA4844658

Type: Binding

Description: Protac activity at CRBN/AR T878A mutant in human LNCaP cells assessed as reduction in AR protein level at 100 nM after 24 hrs in presence of N-((1r,4r)-4-((3-chloro-4-cyanophenyl)(methyl)amino)cyclohexyl)-4-(4-methylpiperazin-1-yl)benzamide by Western blot analysis

Organism: Homo sapiens

Cell type: LNCaP

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
763.303.803.80