Basic Information
ID: ALA4844860
Type: Binding
Description: Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins followed by substrate addition by fluorescence based FDH-coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4844860
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 289.34 | 3.31 | 3.31 |
| 272.26 | 1.17 | 1.17 |
| 251.29 | 2.95 | 2.95 |
| 307.38 | 4.16 | 4.16 |
| 290.33 | 3.43 | 3.43 |
| 214.23 | 1.76 | 1.76 |
| 304.35 | 3.35 | 3.35 |
| 252.28 | 1.94 | 1.94 |
| 265.32 | 2.87 | 2.87 |
| 332.41 | 4.46 | 4.46 |
| 300.32 | 1.87 | 1.87 |
| 285.35 | 1.91 | 1.91 |
| 286.29 | 1.78 | 1.78 |
| 215.26 | 2.01 | 2.01 |
| 299.38 | 2.26 | 2.26 |
| 256.31 | 2.72 | 2.72 |
| 258.24 | 1.08 | 1.08 |
| 300.32 | 1.87 | 1.87 |
| 299.33 | 1.44 | 1.44 |
| 304.35 | 3.44 | 3.44 |
| 313.36 | 1.78 | 1.78 |
| 286.29 | 1.78 | 1.78 |
| 334.33 | 3.13 | 3.13 |
| 286.72 | 3.00 | 3.00 |
| 304.35 | 3.68 | 3.68 |
| 254.29 | 2.49 | 2.49 |
| 213.24 | 1.64 | 1.64 |
| 304.35 | 3.74 | 3.74 |