Basic Information
ID: ALA4845096
Type: Binding
Description: Inhibition of full length human CDK2 (1 to 298 end residues)/N-terminal GST-tagged CyclinA2 (1 to 432 residues) expressed in baculovirus expression system at 100 nM preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK2/Cyclin A2(ALA3038469)
Document: ALA4842385
Inhibition of full length human CDK2 (1 to 298 end residues)/N-terminal GST-tagged CyclinA2 (1 to 432 residues) expressed in baculovirus expression system at 100 nM preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845096
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 277.28 | 2.65 | 2.65 |
| 262.27 | 2.66 | 2.66 |
| 434.50 | 4.04 | 4.04 |
| 392.42 | 2.87 | 2.87 |
| 434.50 | 3.96 | 3.96 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 454.91 | 4.31 | 4.31 |
| 471.31 | 3.63 | 3.63 |
| 450.50 | 3.66 | 3.66 |
| 429.23 | 2.46 | 2.46 |
| 450.50 | 3.66 | 3.66 |
| 363.37 | 3.06 | 3.06 |
| 350.33 | 1.70 | 1.70 |
| 457.28 | 3.24 | 3.24 |
| 438.46 | 3.79 | 3.79 |
| 450.50 | 3.66 | 3.66 |
| 378.39 | 2.48 | 2.48 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 488.47 | 4.67 | 4.67 |
| 546.37 | 4.26 | 4.26 |
| 499.37 | 4.41 | 4.41 |
| 485.34 | 4.02 | 4.02 |
| 454.91 | 4.31 | 4.31 |
| 434.50 | 3.96 | 3.96 |
| 499.37 | 4.41 | 4.41 |
| 416.44 | 2.51 | 2.51 |
| 420.47 | 3.65 | 3.65 |
| 406.44 | 3.26 | 3.26 |