Basic Information
ID: ALA4845097
Type: Binding
Description: Inhibition of full length human CDK4 (1 to 303 residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system at 100 nM preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK4/Cyclin D3(ALA3038472)
Document: ALA4842385
Inhibition of full length human CDK4 (1 to 303 residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system at 100 nM preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845097
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 277.28 | 2.65 | 2.65 |
| 262.27 | 2.66 | 2.66 |
| 434.50 | 4.04 | 4.04 |
| 392.42 | 2.87 | 2.87 |
| 434.50 | 3.96 | 3.96 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 454.91 | 4.31 | 4.31 |
| 471.31 | 3.63 | 3.63 |
| 450.50 | 3.66 | 3.66 |
| 429.23 | 2.46 | 2.46 |
| 450.50 | 3.66 | 3.66 |
| 363.37 | 3.06 | 3.06 |
| 350.33 | 1.70 | 1.70 |
| 457.28 | 3.24 | 3.24 |
| 438.46 | 3.79 | 3.79 |
| 450.50 | 3.66 | 3.66 |
| 378.39 | 2.48 | 2.48 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 488.47 | 4.67 | 4.67 |
| 546.37 | 4.26 | 4.26 |
| 499.37 | 4.41 | 4.41 |
| 485.34 | 4.02 | 4.02 |
| 454.91 | 4.31 | 4.31 |
| 434.50 | 3.96 | 3.96 |
| 499.37 | 4.41 | 4.41 |
| 416.44 | 2.51 | 2.51 |
| 420.47 | 3.65 | 3.65 |
| 406.44 | 3.26 | 3.26 |