Basic Information
ID: ALA4845098
Type: Binding
Description: Inhibition of full length human CDK6 (1 to 326 end residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system at 100 nM preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4845098
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 277.28 | 2.65 | 2.65 |
| 262.27 | 2.66 | 2.66 |
| 434.50 | 4.04 | 4.04 |
| 392.42 | 2.87 | 2.87 |
| 434.50 | 3.96 | 3.96 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 454.91 | 4.31 | 4.31 |
| 471.31 | 3.63 | 3.63 |
| 450.50 | 3.66 | 3.66 |
| 429.23 | 2.46 | 2.46 |
| 450.50 | 3.66 | 3.66 |
| 363.37 | 3.06 | 3.06 |
| 350.33 | 1.70 | 1.70 |
| 457.28 | 3.24 | 3.24 |
| 438.46 | 3.79 | 3.79 |
| 450.50 | 3.66 | 3.66 |
| 378.39 | 2.48 | 2.48 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 488.47 | 4.67 | 4.67 |
| 546.37 | 4.26 | 4.26 |
| 499.37 | 4.41 | 4.41 |
| 485.34 | 4.02 | 4.02 |
| 454.91 | 4.31 | 4.31 |
| 434.50 | 3.96 | 3.96 |
| 499.37 | 4.41 | 4.41 |
| 416.44 | 2.51 | 2.51 |
| 420.47 | 3.65 | 3.65 |
| 406.44 | 3.26 | 3.26 |