Basic Information
ID: ALA4845099
Type: Binding
Description: Inhibition of HDAC in human HeLa nuclear extract at 1000 nM using Boc-Lys(acetyl)-AMC as substrate measured after 1 hr by fluorescence microplate reader assay relative to control
Format: BAO_0000220
Organism: Homo sapiens
Cell type: HeLa
Subcellular Fraction: Nucleus
Target: Histone deacetylase(ALA2093865)
Document: ALA4842385
Inhibition of HDAC in human HeLa nuclear extract at 1000 nM using Boc-Lys(acetyl)-AMC as substrate measured after 1 hr by fluorescence microplate reader assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845099
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 277.28 | 2.65 | 2.65 |
| 262.27 | 2.66 | 2.66 |
| 434.50 | 4.04 | 4.04 |
| 392.42 | 2.87 | 2.87 |
| 434.50 | 3.96 | 3.96 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 454.91 | 4.31 | 4.31 |
| 471.31 | 3.63 | 3.63 |
| 450.50 | 3.66 | 3.66 |
| 429.23 | 2.46 | 2.46 |
| 450.50 | 3.66 | 3.66 |
| 363.37 | 3.06 | 3.06 |
| 350.33 | 1.70 | 1.70 |
| 457.28 | 3.24 | 3.24 |
| 438.46 | 3.79 | 3.79 |
| 450.50 | 3.66 | 3.66 |
| 378.39 | 2.48 | 2.48 |
| 434.50 | 3.96 | 3.96 |
| 465.47 | 3.56 | 3.56 |
| 488.47 | 4.67 | 4.67 |
| 546.37 | 4.26 | 4.26 |
| 499.37 | 4.41 | 4.41 |
| 485.34 | 4.02 | 4.02 |
| 454.91 | 4.31 | 4.31 |
| 434.50 | 3.96 | 3.96 |
| 499.37 | 4.41 | 4.41 |
| 416.44 | 2.51 | 2.51 |
| 420.47 | 3.65 | 3.65 |
| 406.44 | 3.26 | 3.26 |