Basic Information
ID: ALA4845113
Type: Binding
Description: Inhibition of full length human CDK4 (1 to 303 residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4845113
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 335.41 | 2.80 | 2.80 |
| 363.37 | 3.06 | 3.06 |
| 378.39 | 2.48 | 2.48 |
| 416.44 | 2.51 | 2.51 |