Basic Information
ID: ALA4845114
Type: Binding
Description: Inhibition of full length human CDK6 (1 to 326 end residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK6/cyclin D3(ALA2111448)
Document: ALA4842385
Inhibition of full length human CDK6 (1 to 326 end residues)/N-terminal GST-fusion tagged CyclinD3 (1 to 292 residues) expressed in baculovirus expression system preincubated for 10 mins followed by substrate and ATP addition by mobility shift assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 335.41 | 2.80 | 2.80 |
| 363.37 | 3.06 | 3.06 |
| 378.39 | 2.48 | 2.48 |
| 416.44 | 2.51 | 2.51 |