Inhibition of CDK2/4/6 in human A549 cells assessed as decrease in Rb phosphorylation at 10 uM incubated for 24 hrs followed by compound washout by DA...

Basic Information

ID: ALA4845144

Type: Binding

Description: Inhibition of CDK2/4/6 in human A549 cells assessed as decrease in Rb phosphorylation at 10 uM incubated for 24 hrs followed by compound washout by DAPI staining based immunofluorescence assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: A549

Target: Cyclin-dependent kinase 2/4/6(ALA4888444)

Document: ALA4842385

Inhibition of CDK2/4/6 in human A549 cells assessed as decrease in Rb phosphorylation at 10 uM incubated for 24 hrs followed by compound washout by DAPI staining based immunofluorescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4845144

Inhibition

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
378.39	2.48	2.48

Parent Molecular Weight

ALogP

Polar Surface Area

378.39

2.48

Inhibition of CDK2/4/6 in human A549 cells assessed as decrease in Rb phosphorylation at 10 uM incubated for 24 hrs followed by compound washout by DA...

Basic Information

Activity Charts

Compound Summary