Assay Report Card

Basic Information

ID: ALA4845161

Type: Functional

Description: In vivo inhibition of HDAC6 in BALB/c nude mouse xenografted with human A549 cells assessed as increase in alpha tubulin acetylation at 25 to 50 mg/kg, iv administered for 21 consecutive days by immunohistochemical analysis

Organism: Mus musculus

Strain: BALB/c

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
378.392.482.48