Basic Information
ID: ALA4845161
Type: Functional
Description: In vivo inhibition of HDAC6 in BALB/c nude mouse xenografted with human A549 cells assessed as increase in alpha tubulin acetylation at 25 to 50 mg/kg, iv administered for 21 consecutive days by immunohistochemical analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/c
Target: Histone deacetylase 6(ALA2878)
Document: ALA4842385
In vivo inhibition of HDAC6 in BALB/c nude mouse xenografted with human A549 cells assessed as increase in alpha tubulin acetylation at 25 to 50 mg/kg, iv administered for 21 consecutive days by immunohistochemical analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845161
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.39 | 2.48 | 2.48 |