Basic Information
ID: ALA4845162
Type: Functional
Description: In vivo inhibition of CDK2/4/6 in BALB/c nude mouse xenografted with human A549 cells assessed as reduction in Rb phosphorylation at 25 to 50 mg/kg, iv administered for 21 consecutive days by immunohistochemical analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/c
Target: Unchecked(ALA612545)
Document: ALA4842385
In vivo inhibition of CDK2/4/6 in BALB/c nude mouse xenografted with human A549 cells assessed as reduction in Rb phosphorylation at 25 to 50 mg/kg, iv administered for 21 consecutive days by immunohistochemical analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4845162
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.39 | 2.48 | 2.48 |