Basic Information
ID: ALA4845510
Type: ADME
Description: Inhibition of human recombinant CYP2D6 expressed in insect cells using AMMC as substrate preincubated for 30 mins followed by NADPH regenerating system addition and measured after 45 mins by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4845510
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.48 | 3.58 | 3.58 |
| 364.54 | 3.21 | 3.21 |
| 405.59 | 3.03 | 3.03 |
| 405.59 | 3.27 | 3.27 |
| 417.60 | 2.76 | 2.76 |
| 433.64 | 3.64 | 3.64 |
| 420.61 | 2.68 | 2.68 |
| 431.63 | 3.25 | 3.25 |
| 431.63 | 3.10 | 3.10 |
| 419.62 | 3.25 | 3.25 |
| 419.62 | 3.79 | 3.79 |
| 405.59 | 3.27 | 3.27 |
| 431.63 | 3.25 | 3.25 |
| 433.64 | 3.64 | 3.64 |
| 419.62 | 3.25 | 3.25 |