Assay Report Card

Basic Information

ID: ALA5030362

Type: Toxicity

Description: Selectivity index, ratio of EC50 for inhibition of SARS CoV-2 3C like protease expressed in HEK293T cells transfected with pGlo-VRLQS incubated for 6 hrs by firefly/renilla luciferase reporter assay to EC50 for antiviral activity against SARS CoV-2 infected in African green monkey Vero cells assessed as inhibition of viral replication incubated for 48 to 72 hrs by plaque reduction assay

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
507.540.540.54
625.672.912.91
555.672.092.09