Basic Information
ID: ALA5030414
Type: Functional
Description: Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated cAMP production incubated for 30 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Prostanoid EP3 receptor(ALA3710)
Document: ALA5029194
Antagonist activity at human EP3 receptor expressed in CHO-K1 cells assessed as reduction in sulprostone induced inhibition of forskolin stimulated cAMP production incubated for 30 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5030414
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.42 | 5.96 | 5.96 |
| 539.87 | 5.30 | 5.30 |
| 557.86 | 5.60 | 5.60 |
| 569.90 | 5.31 | 5.31 |
| 526.47 | 4.41 | 4.41 |
| 561.52 | 5.86 | 5.86 |
| 598.34 | 6.31 | 6.31 |
| 575.52 | 4.05 | 4.05 |
| 540.50 | 4.72 | 4.72 |
| 535.45 | 4.65 | 4.65 |
| 540.86 | 5.73 | 5.73 |
| 587.89 | 5.61 | 5.61 |
| 587.89 | 5.61 | 5.61 |
| 577.92 | 5.97 | 5.97 |
| 509.42 | 3.38 | 3.38 |
| 597.44 | 6.02 | 6.02 |
| 580.35 | 6.01 | 6.01 |
| 579.51 | 6.16 | 6.16 |
| 511.46 | 4.71 | 4.71 |
| 557.86 | 5.60 | 5.60 |
| 528.44 | 4.05 | 4.05 |
| 535.45 | 4.65 | 4.65 |
| 565.43 | 5.67 | 5.67 |
| 598.55 | 5.64 | 5.64 |
| 581.33 | 6.44 | 6.44 |