In vivo antagonist activity at ER3 receptor in Sprague-Dawley rat assessed as reversal of sulprostone induced reduction in circulating insulin levels ...

Basic Information

ID: ALA5030419

Type: Functional

Description: In vivo antagonist activity at ER3 receptor in Sprague-Dawley rat assessed as reversal of sulprostone induced reduction in circulating insulin levels at 10 times Ki, administered as iv infusion measured up to 30 mins after glucose administration by glucose tolerance test

Format: BAO_0000218

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Target:  Unchecked(ALA612545)

Document:  ALA5029194

In vivo antagonist activity at ER3 receptor in Sprague-Dawley rat assessed as reversal of sulprostone induced reduction in circulating insulin levels at 10 times Ki, administered as iv infusion measured up to 30 mins after glucose administration by glucose tolerance test: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
539.875.305.30