Basic Information
ID: ALA5031411
Type: Binding
Description: Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 10 min in presence of NAD+ followed by addition of substrate and further incubated for 10 mins
Format: BAO_0000219
Organism: Homo sapiens
Target: Methylenetetrahydrofolate dehydrogenase(ALA2541)
Document: ALA5030528
Inhibition of C-terminal His-tagged human MTHFD1 (1 to 306 residues) expressed in insect cells using tetrahydrofolate as substrate preincubated for 10 min in presence of NAD+ followed by addition of substrate and further incubated for 10 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5031411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.31 | 2.10 | 2.10 |
| 474.30 | 3.23 | 3.23 |
| 608.01 | 2.41 | 2.41 |
| 452.34 | 2.50 | 2.50 |
| 463.28 | 3.24 | 3.24 |
| 534.53 | 1.27 | 1.27 |
| 589.39 | 2.19 | 2.19 |
| 592.39 | 2.59 | 2.59 |
| 522.95 | 2.48 | 2.48 |
| 603.42 | 2.58 | 2.58 |
| 520.50 | 0.88 | 0.88 |