Basic Information
ID: ALA5031416
Type: Binding
Description: Uncompetitive inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells assessed as decrease in Vmax using varying levels of tetrahydrofolate as substrate by double-reciprocal plot analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(ALA3621036)
Document: ALA5030528
Uncompetitive inhibition of C-terminal His-tagged human MTHFD2 (36 to 350 residues) expressed in insect cells assessed as decrease in Vmax using varying levels of tetrahydrofolate as substrate by double-reciprocal plot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5031416
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 522.95 | 2.48 | 2.48 |
| 603.42 | 2.58 | 2.58 |