Assay Report Card

Basic Information

ID: ALA5031451

Type: Functional

Description: Inhibition of IL-1beta release in human THP-1 derived macrophages pretreated with NLRP3 inhibitor MCC950 for 1 hr followed by compound addition and measured after 6 hrs by ELISA and immunoblotting analysis

Organism: Homo sapiens

Cell type: Macrophage

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
850.049.889.88