Basic Information
ID: ALA5032406
Type: Binding
Description: Inhibition of human N-terminal His6-tagged KDM2A (M1 to P517 residues) expressed in insect cells using H3K36(Me2) as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by Alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032406
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.34 | 2.19 | 2.19 |
| 242.30 | 1.75 | 1.75 |
| 270.27 | 0.64 | 0.64 |
| 268.34 | 2.14 | 2.14 |
| 262.29 | 1.76 | 1.76 |
| 172.16 | 0.13 | 0.13 |
| 290.30 | 1.44 | 1.44 |
| 228.27 | 1.36 | 1.36 |
| 242.21 | 0.16 | 0.16 |
| 276.32 | 1.80 | 1.80 |
| 186.19 | 0.19 | 0.19 |
| 304.37 | 2.58 | 2.58 |
| 298.41 | 3.31 | 3.31 |