Basic Information
ID: ALA5032408
Type: Binding
Description: Inhibition of human N-terminal His6-tagged KDM4A (M1 to L359 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by Alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032408
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.34 | 2.19 | 2.19 |
| 242.30 | 1.75 | 1.75 |
| 270.27 | 0.64 | 0.64 |
| 268.34 | 2.14 | 2.14 |
| 262.29 | 1.76 | 1.76 |
| 172.16 | 0.13 | 0.13 |
| 290.30 | 1.44 | 1.44 |
| 228.27 | 1.36 | 1.36 |
| 242.21 | 0.16 | 0.16 |
| 276.32 | 1.80 | 1.80 |
| 186.19 | 0.19 | 0.19 |
| 304.37 | 2.58 | 2.58 |
| 298.41 | 3.31 | 3.31 |