Basic Information
ID: ALA5032409
Type: Binding
Description: Inhibition of human N-terminal His6-tagged KDM4D (M1 to G373 residues) expressed in Escherichia coli using H3K9(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 8 mins by Alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032409
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.34 | 2.19 | 2.19 |
| 242.30 | 1.75 | 1.75 |
| 270.27 | 0.64 | 0.64 |
| 268.34 | 2.14 | 2.14 |
| 262.29 | 1.76 | 1.76 |
| 172.16 | 0.13 | 0.13 |
| 290.30 | 1.44 | 1.44 |
| 228.27 | 1.36 | 1.36 |
| 242.21 | 0.16 | 0.16 |
| 276.32 | 1.80 | 1.80 |
| 186.19 | 0.19 | 0.19 |
| 304.37 | 2.58 | 2.58 |
| 298.41 | 3.31 | 3.31 |