Basic Information
ID: ALA5032410
Type: Binding
Description: Inhibition of human N-terminal His6-tagged KDM5B (L882 to S1761 residues) expressed in insect cells using H3K4(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 20 mins by Alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032410
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.34 | 2.19 | 2.19 |
| 242.30 | 1.75 | 1.75 |
| 270.27 | 0.64 | 0.64 |
| 268.34 | 2.14 | 2.14 |
| 262.29 | 1.76 | 1.76 |
| 172.16 | 0.13 | 0.13 |
| 290.30 | 1.44 | 1.44 |
| 228.27 | 1.36 | 1.36 |
| 242.21 | 0.16 | 0.16 |
| 276.32 | 1.80 | 1.80 |
| 186.19 | 0.19 | 0.19 |
| 304.37 | 2.58 | 2.58 |
| 298.41 | 3.31 | 3.31 |