Basic Information
ID: ALA5032411
Type: Binding
Description: Inhibition of human KDM6B (D1141 to R1641 residues) expressed in Escherichia coli using H3K27(Me3) as substrate preincubated for 15 mins followed by substrate addition and measured after 10 mins by Alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.34 | 2.19 | 2.19 |
| 242.30 | 1.75 | 1.75 |
| 270.27 | 0.64 | 0.64 |
| 268.34 | 2.14 | 2.14 |
| 262.29 | 1.76 | 1.76 |
| 172.16 | 0.13 | 0.13 |
| 290.30 | 1.44 | 1.44 |
| 228.27 | 1.36 | 1.36 |
| 242.21 | 0.16 | 0.16 |
| 276.32 | 1.80 | 1.80 |
| 186.19 | 0.19 | 0.19 |
| 304.37 | 2.58 | 2.58 |
| 298.41 | 3.31 | 3.31 |