Basic Information
ID: ALA5032466
Type: Binding
Description: Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5032466
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 803.99 | -0.89 | -0.89 |
| 705.84 | 0.63 | 0.63 |
| 671.83 | 0.44 | 0.44 |
| 629.74 | -0.59 | -0.59 |
| 672.77 | -1.73 | -1.73 |
| 615.72 | -0.98 | -0.98 |
| 685.85 | 0.83 | 0.83 |
| 671.83 | 0.44 | 0.44 |
| 728.88 | -0.96 | -0.96 |
| 721.84 | 0.34 | 0.34 |
| 685.85 | 0.83 | 0.83 |
| 657.80 | 0.05 | 0.05 |
| 689.87 | 0.14 | 0.14 |
| 659.77 | -1.23 | -1.23 |
| 685.85 | 0.78 | 0.78 |
| 686.80 | -1.34 | -1.34 |
| 621.77 | -0.72 | -0.72 |
| 785.97 | 0.36 | 0.36 |