Basic Information
ID: ALA5032643
Type: Functional
Description: Antimalarial activity against chloroquine, pyrimethamine, mefloquine and atovaquone- resistant Plasmodium falciparum TM90-C2B infected in human erythrocytes assessed as reduction in parasite growth incubated for 48 hrs followed by addition of [3H]-hypoxanthine and measured after 24 hrs by Topcount liquid scintillation counting method
Format: BAO_0000218
Organism: Plasmodium falciparum
Strain: TM90-C2B
Cell type: Erythrocyte
Target: Plasmodium falciparum(ALA364)
Document: ALA5032492
Antimalarial activity against chloroquine, pyrimethamine, mefloquine and atovaquone- resistant Plasmodium falciparum TM90-C2B infected in human erythrocytes assessed as reduction in parasite growth incubated for 48 hrs followed by addition of [3H]-hypoxanthine and measured after 24 hrs by Topcount liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5032643
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 284.35 | 2.19 | 2.19 |
| 30.03 | -0.18 | -0.18 |
| 366.84 | 5.51 | 5.51 |
| 313.78 | 4.47 | 4.47 |
| 495.40 | 5.28 | 5.28 |
| 549.37 | 5.99 | 5.99 |
| 535.35 | 5.60 | 5.60 |
| 369.85 | 5.50 | 5.50 |
| 481.38 | 4.89 | 4.89 |
| 385.85 | 5.72 | 5.72 |
| 410.90 | 5.78 | 5.78 |
| 412.92 | 6.02 | 6.02 |
| 115.13 | 0.46 | 0.46 |