Basic Information
ID: ALA5032820
Type: Binding
Description: Inhibition of RPE65 in bovine retinal pigment epithelium microsomes assessed as decrease of 11-cis-retinol using trans-retinol measured after 1 hr by normal phase HPLC analysis
Organism: Bos taurus
Tissue: Retina
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5032820
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.45 | 3.97 | 3.97 |
| 263.38 | 3.03 | 3.03 |
| 297.41 | 3.80 | 3.80 |
| 301.37 | 3.27 | 3.27 |
| 281.37 | 3.17 | 3.17 |
| 297.41 | 3.80 | 3.80 |
| 299.36 | 3.27 | 3.27 |
| 281.37 | 3.17 | 3.17 |
| 321.44 | 4.11 | 4.11 |
| 265.39 | 3.03 | 3.03 |
| 297.41 | 3.80 | 3.80 |
| 297.41 | 3.80 | 3.80 |
| 281.37 | 3.17 | 3.17 |
| 321.44 | 4.11 | 4.11 |
| 281.37 | 3.17 | 3.17 |
| 321.44 | 4.11 | 4.11 |
| 321.44 | 4.11 | 4.11 |
| 297.41 | 3.80 | 3.80 |