Assay Report Card

Basic Information

ID: ALA5033030

Type: Binding

Description: Inverse agonist activity at full length TLX activating element expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as fold decrease in reporter activity at 100 uM by luciferase reporter gene assay relative to control

Organism: Homo sapiens

Cell type: HEK293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
172.231.811.81
217.271.541.54
166.14-1.05-1.05
210.243.003.00
186.261.981.98
194.262.292.29
145.161.211.21
214.651.291.29