Basic Information
ID: ALA5033310
Type: Binding
Description: Inhibition of N-terminal his-tagged GCN4 leucine zipper fused human MALT1 (340-281 residues) expressed in Escherichia coli using Ac-LVSR-AMC as substrate by HTS assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5033310
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.59 | 5.89 | 5.89 |
| 462.35 | 4.60 | 4.60 |
| 492.38 | 4.60 | 4.60 |
| 456.46 | 3.52 | 3.52 |
| 452.38 | 4.33 | 4.33 |
| 381.48 | 4.44 | 4.44 |
| 492.38 | 4.60 | 4.60 |
| 480.35 | 4.92 | 4.92 |
| 432.87 | 4.39 | 4.39 |
| 415.93 | 5.09 | 5.09 |
| 445.91 | 4.51 | 4.51 |
| 436.35 | 4.81 | 4.81 |
| 415.93 | 5.04 | 5.04 |
| 417.46 | 4.66 | 4.66 |
| 422.32 | 5.13 | 5.13 |
| 387.87 | 4.48 | 4.48 |
| 401.90 | 4.79 | 4.79 |
| 431.93 | 4.16 | 4.16 |
| 381.48 | 4.39 | 4.39 |
| 498.41 | 5.37 | 5.37 |
| 482.37 | 5.15 | 5.15 |
| 449.46 | 4.12 | 4.12 |
| 450.31 | 4.73 | 4.73 |
| 460.38 | 5.15 | 5.15 |
| 431.88 | 4.18 | 4.18 |
| 490.91 | 4.17 | 4.17 |
| 381.48 | 4.39 | 4.39 |
| 481.96 | 4.85 | 4.85 |
| 395.51 | 4.69 | 4.69 |
| 431.47 | 3.98 | 3.98 |
| 460.38 | 5.20 | 5.20 |
| 443.51 | 3.85 | 3.85 |
| 383.45 | 3.83 | 3.83 |
| 423.95 | 4.90 | 4.90 |
| 387.87 | 4.48 | 4.48 |
| 480.80 | 4.92 | 4.92 |
| 471.52 | 3.63 | 3.63 |
| 395.51 | 4.75 | 4.75 |
| 436.31 | 3.86 | 3.86 |
| 467.32 | 5.04 | 5.04 |
| 445.91 | 4.26 | 4.26 |
| 398.43 | 3.73 | 3.73 |
| 431.93 | 4.16 | 4.16 |
| 456.76 | 5.78 | 5.78 |
| 413.48 | 3.84 | 3.84 |
| 475.98 | 5.27 | 5.27 |
| 439.52 | 4.17 | 4.17 |
| 542.86 | 5.48 | 5.48 |
| 501.21 | 5.89 | 5.89 |
| 476.33 | 4.28 | 4.28 |
| 479.57 | 5.58 | 5.58 |
| 488.98 | 4.59 | 4.59 |
| 434.92 | 5.59 | 5.59 |
| 353.43 | 3.82 | 3.82 |
| 425.49 | 3.92 | 3.92 |
| 480.35 | 4.92 | 4.92 |
| 443.51 | 3.85 | 3.85 |
| 473.53 | 3.86 | 3.86 |
| 383.45 | 3.83 | 3.83 |
| 476.38 | 4.27 | 4.27 |
| 422.32 | 5.13 | 5.13 |
| 531.97 | 5.73 | 5.73 |
| 531.97 | 5.73 | 5.73 |
| 405.86 | 4.62 | 4.62 |
| 383.45 | 3.83 | 3.83 |
| 447.44 | 3.89 | 3.89 |
| 417.90 | 4.49 | 4.49 |
| 487.56 | 5.28 | 5.28 |
| 447.93 | 4.49 | 4.49 |
| 492.64 | 5.77 | 5.77 |
| 447.93 | 4.49 | 4.49 |