Basic Information
ID: ALA5033748
Type: Toxicity
Description: Selectivity index, ratio of IC50 for cytotoxicity against African green monkey Vero cells to IC50 for antitrypanosomal activity against Trypanosoma brucei rhodesiense STI B900
Activity Charts
Bioactivity
Activity Types for Assay ALA5033748
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.69 | 3.03 | 3.03 |
| 359.47 | 4.97 | 4.97 |
| 254.33 | 3.64 | 3.64 |
| 332.36 | 1.74 | 1.74 |
| 379.43 | 4.68 | 4.68 |
| 329.44 | 4.92 | 4.92 |
| 253.34 | 3.25 | 3.25 |
| 239.32 | 3.47 | 3.47 |
| 299.37 | 2.75 | 2.75 |
| 345.44 | 4.41 | 4.41 |
| 421.54 | 5.98 | 5.98 |
| 345.44 | 4.76 | 4.76 |
| 367.88 | 4.07 | 4.07 |
| 370.67 | 3.16 | 3.16 |
| 269.34 | 2.74 | 2.74 |
| 361.44 | 4.54 | 4.54 |
| 283.37 | 3.05 | 3.05 |
| 289.42 | 3.87 | 3.87 |
| 449.55 | 6.28 | 6.28 |
| 348.24 | 3.51 | 3.51 |
| 289.42 | 3.51 | 3.51 |
| 375.47 | 4.42 | 4.42 |
| 299.42 | 5.01 | 5.01 |
| 345.44 | 4.31 | 4.31 |
| 273.42 | 4.02 | 4.02 |
| 334.21 | 3.16 | 3.16 |
| 395.50 | 5.56 | 5.56 |
| 314.34 | 2.65 | 2.65 |
| 348.24 | 3.51 | 3.51 |
| 306.41 | 1.27 | 1.27 |
| 370.67 | 3.16 | 3.16 |
| 305.81 | 2.71 | 2.71 |
| 347.54 | 5.47 | 5.47 |
| 291.78 | 2.40 | 2.40 |
| 297.40 | 3.18 | 3.18 |
| 269.34 | 2.74 | 2.74 |
| 255.32 | 2.40 | 2.40 |
| 283.37 | 2.79 | 2.79 |
| 449.55 | 6.28 | 6.28 |
| 275.39 | 3.17 | 3.17 |
| 379.89 | 5.06 | 5.06 |
| 379.89 | 5.06 | 5.06 |
| 290.41 | 1.78 | 1.78 |
| 421.54 | 5.54 | 5.54 |
| 273.38 | 4.49 | 4.49 |
| 375.47 | 4.42 | 4.42 |
| 331.42 | 4.07 | 4.07 |
| 283.37 | 3.05 | 3.05 |
| 255.32 | 2.44 | 2.44 |
| 269.34 | 2.71 | 2.71 |
| 417.63 | ||
| 345.44 | 4.41 | 4.41 |
| 275.39 | 3.12 | 3.12 |
| 331.42 | 4.11 | 4.11 |
| 511.67 | 8.30 | 8.30 |
| 223.32 | 3.34 | 3.34 |
| 299.37 | 2.62 | 2.62 |
| 315.42 | 5.13 | 5.13 |
| 379.89 | 5.06 | 5.06 |
| 289.42 | 3.51 | 3.51 |
| 399.62 | 6.51 | 6.51 |
| 421.54 | 6.08 | 6.08 |
| 363.43 | 4.55 | 4.55 |
| 311.85 | 3.17 | 3.17 |