Basic Information
ID: ALA5033752
Type: Functional
Description: Antagonist activity at human CXCR2 expressed in HEK293 cells assessed as inhibition of CXCL8-induced beta-arrestin recruitment preincubated for 30 mins followed by addition of agonist incubated for 90 mins by beta arrestin assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5033752
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.67 | 3.64 | 3.64 |
| 461.29 | 3.04 | 3.04 |
| 348.36 | 2.98 | 2.98 |
| 380.85 | 3.72 | 3.72 |
| 399.25 | 4.14 | 4.14 |
| 409.26 | 3.60 | 3.60 |
| 418.86 | 2.85 | 2.85 |
| 409.26 | 3.60 | 3.60 |
| 346.41 | 3.06 | 3.06 |
| 382.80 | 3.63 | 3.63 |
| 416.84 | 2.93 | 2.93 |
| 364.81 | 3.49 | 3.49 |
| 411.28 | 3.52 | 3.52 |
| 415.25 | 3.70 | 3.70 |
| 378.38 | 2.84 | 2.84 |
| 384.82 | 3.55 | 3.55 |
| 398.36 | 3.86 | 3.86 |
| 434.83 | 3.07 | 3.07 |
| 401.27 | 4.06 | 4.06 |
| 350.37 | 2.90 | 2.90 |
| 416.43 | 2.64 | 2.64 |
| 453.30 | 3.50 | 3.50 |
| 378.84 | 3.80 | 3.80 |
| 366.83 | 3.41 | 3.41 |
| 436.85 | 2.99 | 2.99 |
| 362.38 | 3.28 | 3.28 |
| 411.28 | 3.52 | 3.52 |
| 414.41 | 2.72 | 2.72 |
| 399.25 | 4.14 | 4.14 |
| 463.31 | 2.96 | 2.96 |
| 344.39 | 3.15 | 3.15 |
| 451.29 | 3.58 | 3.58 |
| 364.40 | 3.20 | 3.20 |
| 401.27 | 4.06 | 4.06 |
| 400.38 | 3.77 | 3.77 |