Basic Information
ID: ALA5034161
Type: Functional
Description: Positive allosteric modulator activity at human mGlu2 receptor expressed in rat Chem-1 cells assessed as cytosolic Ca2+ ion concentration measured after 30 mins by fluorometric analysis
Organism: Homo sapiens
Cell type: Chem-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5034161
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.43 | 4.63 | 4.63 |
| 356.27 | 3.86 | 3.86 |
| 419.40 | 4.25 | 4.25 |
| 374.21 | 3.59 | 3.59 |
| 286.29 | 1.81 | 1.81 |
| 435.12 | 4.22 | 4.22 |
| 335.38 | 3.71 | 3.71 |
| 334.22 | 3.05 | 3.05 |
| 317.39 | 3.57 | 3.57 |
| 320.19 | 2.66 | 2.66 |
| 309.29 | 2.92 | 2.92 |
| 187.20 | 0.78 | 0.78 |
| 241.29 | 1.90 | 1.90 |
| 335.38 | 3.71 | 3.71 |
| 379.77 | 4.36 | 4.36 |
| 275.74 | 2.56 | 2.56 |
| 356.22 | 3.45 | 3.45 |
| 390.67 | 4.11 | 4.11 |
| 323.32 | 3.31 | 3.31 |
| 408.66 | 4.25 | 4.25 |
| 391.66 | 3.50 | 3.50 |
| 374.21 | 3.59 | 3.59 |
| 453.11 | 4.36 | 4.36 |
| 351.84 | 4.22 | 4.22 |
| 410.83 | 3.36 | 3.36 |
| 363.38 | 3.95 | 3.95 |