Basic Information
ID: ALA5034988
Type: Binding
Description: Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed by 5-FAM-QEDIIIINIARHLAQVGDSMD-RSIPPG tracer addition and measured after 20 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5034988
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 850.05 | 6.05 | 6.05 |
| 636.58 | 7.15 | 7.15 |
| 703.68 | 7.88 | 7.88 |
| 677.67 | 6.92 | 6.92 |
| 675.63 | 7.06 | 7.06 |
| 677.67 | 6.92 | 6.92 |
| 594.50 | 6.03 | 6.03 |
| 661.60 | 6.76 | 6.76 |
| 594.50 | 6.03 | 6.03 |
| 661.60 | 6.76 | 6.76 |
| 585.73 | 5.20 | 5.20 |
| 584.63 | 4.94 | 4.94 |
| 568.63 | 5.22 | 5.22 |
| 584.63 | 4.94 | 4.94 |
| 600.70 | 5.10 | 5.10 |
| 568.70 | 5.17 | 5.17 |
| 584.70 | 5.39 | 5.39 |
| 558.15 | 5.91 | 5.91 |
| 747.81 | 8.65 | 8.65 |
| 568.70 | 5.17 | 5.17 |
| 703.68 | 7.67 | 7.67 |
| 608.53 | 6.33 | 6.33 |
| 594.50 | 6.03 | 6.03 |
| 536.68 | 5.51 | 5.51 |
| 537.66 | 5.10 | 5.10 |
| 661.60 | 6.76 | 6.76 |
| 677.67 | 6.92 | 6.92 |
| 691.70 | 7.23 | 7.23 |
| 600.70 | 5.10 | 5.10 |
| 719.75 | 8.04 | 8.04 |
| 618.05 | 5.78 | 5.78 |