Basic Information
ID: ALA5035013
Type: Binding
Description: Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) at up to 100 uM preincubated for 30 mins followed by 5-FAM-QEDIIIINIARHLAQVGDSMD-RSIPPG tracer addition and measured after 20 mins by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5035013
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 850.05 | 6.05 | 6.05 |
| 659.63 | 6.84 | 6.84 |
| 636.58 | 7.15 | 7.15 |
| 703.68 | 7.88 | 7.88 |
| 719.60 | 7.16 | 7.16 |
| 589.12 | 6.03 | 6.03 |
| 552.63 | 5.00 | 5.00 |
| 613.63 | 5.13 | 5.13 |
| 643.63 | 7.13 | 7.13 |
| 677.67 | 6.92 | 6.92 |
| 675.63 | 7.06 | 7.06 |
| 659.70 | 7.30 | 7.30 |
| 592.53 | 6.11 | 6.11 |
| 585.73 | 5.20 | 5.20 |
| 584.70 | 4.87 | 4.87 |
| 731.74 | 8.49 | 8.49 |
| 584.63 | 4.94 | 4.94 |
| 569.66 | 5.04 | 5.04 |
| 568.63 | 5.22 | 5.22 |
| 535.69 | 5.71 | 5.71 |
| 628.75 | 5.92 | 5.92 |
| 584.63 | 4.94 | 4.94 |
| 651.65 | 6.24 | 6.24 |
| 611.66 | 5.74 | 5.74 |
| 600.70 | 5.10 | 5.10 |
| 652.49 | 6.43 | 6.43 |
| 628.60 | 5.03 | 5.03 |
| 667.72 | 6.40 | 6.40 |
| 576.72 | 4.27 | 4.27 |
| 568.70 | 5.17 | 5.17 |
| 656.81 | 6.52 | 6.52 |
| 675.70 | 7.00 | 7.00 |
| 584.70 | 5.39 | 5.39 |
| 558.15 | 5.91 | 5.91 |
| 747.81 | 8.65 | 8.65 |
| 553.66 | 4.81 | 4.81 |
| 558.15 | 5.91 | 5.91 |
| 664.63 | 7.75 | 7.75 |
| 690.67 | 7.42 | 7.42 |
| 568.70 | 5.17 | 5.17 |
| 613.63 | 5.13 | 5.13 |
| 576.53 | 6.40 | 6.40 |
| 703.68 | 7.67 | 7.67 |
| 705.72 | 7.53 | 7.53 |
| 608.53 | 6.33 | 6.33 |
| 576.72 | 4.27 | 4.27 |
| 560.65 | 4.11 | 4.11 |
| 594.50 | 6.03 | 6.03 |
| 585.73 | 5.20 | 5.20 |
| 560.65 | 4.11 | 4.11 |
| 651.65 | 6.24 | 6.24 |
| 536.68 | 5.51 | 5.51 |
| 537.66 | 5.10 | 5.10 |
| 661.60 | 6.76 | 6.76 |
| 691.70 | 7.23 | 7.23 |
| 600.70 | 5.10 | 5.10 |
| 584.55 | 5.50 | 5.50 |
| 644.62 | 6.93 | 6.93 |
| 537.66 | 5.10 | 5.10 |
| 569.66 | 5.04 | 5.04 |
| 584.70 | 4.87 | 4.87 |
| 543.07 | 5.54 | 5.54 |
| 574.15 | 5.62 | 5.62 |
| 551.69 | 5.42 | 5.42 |
| 618.05 | 5.78 | 5.78 |