Basic Information
ID: ALA5035499
Type: Binding
Description: Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5035499
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.45 | 2.59 | 2.59 |
| 384.49 | 4.39 | 4.39 |
| 336.40 | 3.62 | 3.62 |
| 309.39 | 4.50 | 4.50 |
| 468.63 | 3.96 | 3.96 |
| 338.39 | 2.80 | 2.80 |
| 318.38 | 2.42 | 2.42 |
| 431.61 | 3.07 | 3.07 |
| 430.55 | 1.72 | 1.72 |
| 485.59 | 4.30 | 4.30 |
| 494.64 | 4.59 | 4.59 |
| 512.70 | 3.77 | 3.77 |
| 514.67 | 2.61 | 2.61 |
| 479.63 | 4.06 | 4.06 |
| 513.64 | 5.08 | 5.08 |
| 424.51 | 3.01 | 3.01 |
| 550.77 | 5.68 | 5.68 |
| 389.50 | 2.74 | 2.74 |
| 521.67 | 3.03 | 3.03 |
| 542.68 | 6.00 | 6.00 |
| 480.61 | 4.21 | 4.21 |
| 550.66 | 5.87 | 5.87 |
| 417.51 | 2.12 | 2.12 |
| 457.62 | 4.08 | 4.08 |
| 474.57 | 4.30 | 4.30 |
| 506.65 | 4.74 | 4.74 |
| 486.66 | 3.23 | 3.23 |
| 485.67 | 4.86 | 4.86 |
| 520.68 | 5.13 | 5.13 |
| 471.65 | 4.47 | 4.47 |
| 560.67 | 5.52 | 5.52 |
| 482.65 | 3.98 | 3.98 |
| 551.65 | 5.26 | 5.26 |
| 477.61 | 3.82 | 3.82 |
| 508.62 | 3.11 | 3.11 |
| 460.54 | 4.27 | 4.27 |
| 375.47 | 2.35 | 2.35 |
| 466.59 | 3.34 | 3.34 |
| 557.70 | 4.76 | 4.76 |
| 506.65 | 4.74 | 4.74 |
| 498.67 | 3.42 | 3.42 |
| 416.53 | 1.70 | 1.70 |
| 549.72 | 4.28 | 4.28 |
| 532.62 | 4.74 | 4.74 |
| 528.66 | 5.61 | 5.61 |
| 511.64 | 4.87 | 4.87 |
| 444.58 | 2.11 | 2.11 |
| 514.63 | 5.22 | 5.22 |
| 522.72 | 4.90 | 4.90 |
| 452.56 | 3.79 | 3.79 |
| 513.69 | 2.18 | 2.18 |
| 459.59 | 2.93 | 2.93 |
| 494.64 | 4.12 | 4.12 |
| 483.59 | 4.09 | 4.09 |
| 525.63 | 3.86 | 3.86 |
| 502.62 | 5.08 | 5.08 |
| 403.53 | 3.13 | 3.13 |
| 536.75 | 5.29 | 5.29 |
| 510.71 | 5.08 | 5.08 |
| 480.61 | 3.73 | 3.73 |
| 512.70 | 3.62 | 3.62 |
| 496.68 | 4.37 | 4.37 |
| 543.67 | 4.42 | 4.42 |
| 491.64 | 4.21 | 4.21 |
| 498.67 | 3.28 | 3.28 |
| 492.62 | 3.42 | 3.42 |
| 568.65 | 6.01 | 6.01 |
| 534.71 | 5.38 | 5.38 |
| 542.68 | 5.39 | 5.39 |
| 534.71 | 5.52 | 5.52 |
| 524.64 | 3.43 | 3.43 |
| 521.67 | 3.50 | 3.50 |
| 500.69 | 3.62 | 3.62 |
| 430.55 | 2.04 | 2.04 |
| 497.62 | 4.48 | 4.48 |
| 499.62 | 4.69 | 4.69 |
| 499.66 | 3.85 | 3.85 |
| 472.63 | 2.84 | 2.84 |
| 487.60 | 4.54 | 4.54 |
| 542.68 | 5.86 | 5.86 |
| 507.64 | 2.69 | 2.69 |
| 538.67 | 3.77 | 3.77 |
| 499.66 | 3.71 | 3.71 |
| 431.54 | 2.15 | 2.15 |
| 527.71 | 2.53 | 2.53 |
| 492.62 | 4.35 | 4.35 |
| 528.66 | 5.52 | 5.52 |
| 488.59 | 4.69 | 4.69 |
| 458.61 | 2.50 | 2.50 |
| 472.63 | 2.84 | 2.84 |
| 505.66 | 4.60 | 4.60 |
| 466.59 | 3.82 | 3.82 |