Basic Information
ID: ALA5035545
Type: Binding
Description: Reversal of Pgp-mediated paclitaxel resistance in human LCC6MDR cells assessed as paclitaxel IC50 at 1 uM after 5 days by Cell Titer-Glo luminescence assay (Rvb = 152.5 +/- 9.7 uM)
Organism: Homo sapiens
Cell type: LCC6MDR
Activity Charts
Bioactivity
Activity Types for Assay ALA5035545
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 458.38 | 2.23 | 2.23 |
| 794.67 | 3.99 | 3.99 |
| 570.59 | 4.66 | 4.66 |
| 346.38 | 2.76 | 2.76 |
| 376.41 | 2.77 | 2.77 |
| 596.63 | 5.06 | 5.06 |
| 733.74 | 6.45 | 6.45 |
| 677.68 | 6.04 | 6.04 |
| 707.70 | 6.05 | 6.05 |
| 376.41 | 2.77 | 2.77 |
| 570.59 | 4.66 | 4.66 |
| 596.63 | 5.06 | 5.06 |
| 677.68 | 6.04 | 6.04 |
| 707.70 | 6.05 | 6.05 |
| 733.74 | 6.45 | 6.45 |
| 540.57 | 4.65 | 4.65 |
| 776.81 | 5.74 | 5.74 |
| 570.59 | 4.66 | 4.66 |
| 596.63 | 5.06 | 5.06 |
| 789.85 | 5.66 | 5.66 |
| 753.78 | 7.61 | 7.61 |
| 346.38 | 2.76 | 2.76 |
| 707.70 | 5.40 | 5.40 |
| 667.75 | 5.26 | 5.26 |
| 637.73 | 5.25 | 5.25 |
| 637.73 | 5.25 | 5.25 |
| 566.60 | 5.05 | 5.05 |
| 774.84 | 6.90 | 6.90 |
| 673.69 | 6.43 | 6.43 |
| 566.60 | 5.05 | 5.05 |
| 596.63 | 5.06 | 5.06 |
| 536.58 | 5.04 | 5.04 |
| 667.75 | 5.26 | 5.26 |
| 681.74 | 4.90 | 4.90 |
| 637.73 | 5.25 | 5.25 |
| 607.70 | 5.24 | 5.24 |
| 376.41 | 2.77 | 2.77 |
| 607.70 | 5.24 | 5.24 |
| 647.65 | 6.03 | 6.03 |
| 637.73 | 5.25 | 5.25 |
| 703.72 | 6.44 | 6.44 |
| 376.41 | 2.77 | 2.77 |
| 707.70 | 6.05 | 6.05 |
| 677.68 | 6.04 | 6.04 |
| 570.59 | 4.66 | 4.66 |
| 637.73 | 5.25 | 5.25 |
| 677.68 | 6.04 | 6.04 |
| 663.65 | 5.74 | 5.74 |
| 540.57 | 4.65 | 4.65 |
| 637.73 | 5.25 | 5.25 |
| 770.60 | 6.81 | 6.81 |
| 707.70 | 6.05 | 6.05 |
| 681.74 | 4.90 | 4.90 |