Assay Report Card

Basic Information

ID: ALA5035582

Type: Binding

Description: Induction of human tyrosinase degradation in human A-375 cells assessed as downregulation of tyrosinase at 100 uM pretreated with ubiquitin activating enzyme inhibitor MLN492 for 30 mins followed by compound addition and measured after 24 hrs by immunoblotting analysis

Organism: Homo sapiens

Cell type: A-375

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
537.570.770.77