Basic Information
ID: ALA5035587
Type: Binding
Description: Protac activity at CRBN E3 ubiquitin ligase/tyrosinase in human A375 cells assessed as induction of tyrosinase degradation at 50 uM measured after 24 hrs by immunoblotting analysis relative to control
Organism: Homo sapiens
Cell type: A-375
Activity Charts
Bioactivity
Activity Types for Assay ALA5035587
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 583.60 | -0.37 | -0.37 |
| 551.60 | 1.16 | 1.16 |
| 539.55 | -0.39 | -0.39 |
| 607.71 | 2.72 | 2.72 |
| 495.49 | -0.40 | -0.40 |
| 565.63 | 1.55 | 1.55 |
| 523.55 | 0.38 | 0.38 |
| 509.52 | -0.01 | -0.01 |
| 537.57 | 0.77 | 0.77 |
| 579.65 | 1.94 | 1.94 |