Basic Information
ID: ALA5035892
Type: Functional
Description: Anti-fibrotic activity in Sprague-Dawley rat model of bleomycin-induced lung fibrosis assessed as decrease in bleomycin-induced collagen deposition by measuring decrease in PSR-stained lung sections at 30 mg/kg, po BID for 21 days followed by tracheal administration of bleomycin by PSR staining based HALO densitometric analysis relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA5035892
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 482.54 | 6.74 | 6.74 |
| 471.56 | 3.58 | 3.58 |