Basic Information
ID: ALA5036178
Type: Binding
Description: Binding affinity to N-terminal His6-tagged VHL (54 to 213 residues)/BRD4 BD2 (333 to 460 residues) (unknown origin) expressed in Escherichia coli assessed as displacement of HIF-1alpha preincubated with Brd4 BD2 by ternary binding competitive fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5036178
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 986.66 | 6.53 | 6.53 |
| 1002.66 | ||
| 972.63 | 5.97 | 5.97 |
| 1000.69 | ||
| 973.62 | 6.40 | 6.40 |
| 1003.64 | ||
| 1001.67 | ||
| 987.65 | 6.96 | 6.96 |